Your partner for product development

Test your ideas with us. We are ready to help you in the development of your new products, formulas or processes. Our application center is located in Budapest, Hungary. By working with us your project will be supported by our deep knowledge and valuable expertise in the field.

We have all the necessary equipment from feeding raw materials to post-processing and analytics.

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Hot Melt Extrusion

Melt extrusion is used for enhancing the solubility of poorly soluble drugs by creating amorphous solid dispersions. Continuous formulation method offers a good chance for process control. Thanks to our co-developed lab-scale extruder you can minimize your material cost by reducing the amount of API needed for feasibility studies. The continuously produced extrudate can be ground and homogenized with excipients before tableting. We are ready to investigate melt extrusion of different materials on our new lab-scale, GMP twin-screw extruder developed together with Quick2000 Ltd.

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Wet Granulation

Wet granulation is fundamentally a batch process, which can be divided into two types: high shear and fluid bed granulation. In the course of wet granulation small and/or irregular shaped particles (eg needle crystals) are cohered together with the help of a granulation liquid (usually water or a certain alcohol) and a binder material (eg polyvinylpyrrolidone) to form larger and more spherical particles. The main purpose of the granulation is to improve the flowability and increase the bulk density of the powder to facilitate the tableting process.

The batch type wet granulations are foreseen to be replaced by continuous wet granulation in the pharmaceutical industry in the near future. The shift from batch to continuous technologies has been recommended by the Food and Drug Administration. This continuous wet granulation technology can be carried out on a twin-screw extruder into which solid materials and water can be fed at various parts. In the extruder the materials are mixed and granulated due to the intermesh of the screws, especially at the kneading elements. We are ready and eager to investigate continuous wet granulation of your material on our lab-scale, GMP compatible extruder.